Work

A Rare Presentation of Priapism From Pegylated Filgrastim During Treatment of Urothelial Cancer in an African-American Patient With Sickle Cell Trait

Year: 2025

Type: article

Abstract: Priapism is a complication of sickle cell disease resulting in organ-threatening vaso-occlusive crisis and has been reported rarely in patients with sickle cell trait. We report a case of a patient with urothelial carcinoma undergoing chemotherapy and growth factor support with pegylated filgrastim with stuttering priapism triggered by pegylated filgrastim. This is the first case reported, to our knowledge, of stuttering priapism triggered by pegylated filgrastim, and we hope to raise awareness of this potentially organ-threatening complication in this vulnerable population.

Source: Cureus

DOI: 10.7759/cureus.84492

Authors: Nikhita Kathuria-Prakash, Leland Damron, Sandy C Hernandez, Steven D Hart, Alexandra Drakaki

Institution: University of California, Los Angeles

Language: English

Topic: Hemoglobinopathies and Related Disorders

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4410532105