Work

Lymphadenitis caused by Legionella sainthelensi infection: a case report and literature review

Year: 2025

Type: article

Abstract: Background Legionella infection is a group of bacterial diseases caused by species of the Legionella genus, the most notable of them being Legionnaires’ disease and Pontiac fever. Legionnaires’ disease primarily affects the lungs, with the respiratory and gastrointestinal systems being the most commonly affected. Legionella may cause multisystem involvement, according to this study. In this report, we present a rare case of lymphadenitis caused by Legionella sainthelensi, aiming to raise awareness of atypical manifestations and uncommon sites of Legionella infection. Case presentation We present the case of a 43-year-old man who was admitted to the hospital for a week due to fever and enlargement of the cervical lymph nodes. He was diagnosed with L. sainthelensi lymphadenitis, which was treated with azithromycin and lymph node puncture and drainage. Conclusion For patients with Legionella lymphadenitis, multiple etiological tests should be performed as early as possible to confirm the infectious pathogen. Early intervention with appropriate intravenous antibiotics and lymph node drainage is critical to improve the cure rate.

Source: Frontiers in Medicine

DOI: 10.3389/fmed.2025.1574205

Authors: Cangjian Zhang, Minlei Zhao

Institution: Lishui Central Hospital

Language: English

Topic: Legionella and Acanthamoeba research

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801