Work

Normal variation in brain volumetrics, CSF dynamics, and ocular structures from magnetic resonance images of healthy participants over two years

Year: 2025

Type: article

Abstract: We report estimated thresholds of normal variability from methodological and physiological sources in brain and ocular outcomes in healthy participants. Outcomes that exceed these thresholds have less than a 5% probability of occurring due to these sources of variation. One of the present findings suggests that about 50% of the spaceflight-induced increase in lateral ventricular volume exceeds contributions of expected sources of measurement variability.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00596.2024