Umbilical cord stem cells as regenerative therapy: advances in the treatment of type I diabetes
Year: 2025
Type: article
Abstract: Type I diabetes mellitus was presented as an autoimmune disease that destroyed the β cells of the pancreas, generating an insulin deficit and metabolic complications. Although traditional insulin treatment was necessary, it failed to stop the progression of the disease. Regenerative medicine offered new alternatives, including the use of stem cells derived from the umbilical cord. These cells showed an ability to differentiate into pancreatic cells and modulate the immune system, which helped to improve glycaemic control and reduce dependence on exogenous insulin. Clinical studies confirmed that this therapy was safe, well-tolerated and ethically acceptable, making it a promising alternative in the treatment of T1D.
Source: South Health and Policy
DOI: 10.56294/shp2025212
Authors: Daniela Villada Escobar, Karina Bustamante Galarza
Institution: Universidad Abierta Interamericana
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4410601010