Factors influencing postoperative complications in patients with gastric cancer: A retrospective study
Year: 2025
Type: article
Study design: Observational Study
Abstract: BACKGROUND: Gastric cancer is a malignancy with high morbidity and mortality rates. Surgical intervention, particularly gastrectomy, is essential for curative treatment but carries a substantial risk of complications. Identifying key risk factors and understanding complication profiles are crucial for improving outcomes and guiding perioperative management. AIM: To analyze the incidence of postoperative complications in patients with gastric cancer and identify potential risk factors. METHODS: We conducted a retrospective analysis of 500 patients who underwent gastrectomy between January 2018 and December 2022. Postoperative complications were classified using the Clavien-Dindo system. RESULTS: The overall complication rate was 28.4% (142/500), with 15.2% (76/500) experiencing major complications (Clavien-Dindo grade ≥ III). Pulmonary complications were the most frequent (10.8%), followed by surgical site infections (8.6%), and anastomotic leakage (4.2%). Age 70 years or more, body mass index of 25 kg/m² or more, advanced tumor stage, total gastrectomy, and operative time 240 min or more emerged as independent risk factors. CONCLUSION: Focused preoperative risk assessment, targeted interventions, and reduced operative time for older or obese patients requiring total gastrectomy or presenting with advanced disease are important to improve surgical outcomes.
Authors: Ying Xiao, Bang-Chun Ren, Tao Zhang, Dong Peng, Jiang Min
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4410610320