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An infant with Kawasaki disease having gastrointestinal bleeding due to multiple gastric ulcers

Year: 2025

Type: article

Abstract: Kawasaki disease (KD) is an acute systemic vasculitis managed mainly through intravenous immunoglobulin (IVIG), aspirin, and steroids. Although gastrointestinal symptoms are common, gastrointestinal bleeding is rare. We present the case of an 11-month-old girl with incomplete KD who developed severe gastrointestinal bleeding due to multiple gastric ulcers, despite prophylactic H2-receptor antagonist therapy, requiring blood transfusion therapy. This case illustrates that gastrointestinal bleeding can occur as a direct consequence of KD and from the combined effects of corticosteroids and nonsteroidal anti-inflammatory drugs. It emphasizes the need for vigilant monitoring and further research to efficiently prevent gastrointestinal bleeding in patients with KD.

Source: Journal of General and Family Medicine

DOI: 10.1002/jgf2.70035

Authors: Takeru Kanazawa, Tomokazu Nakagami, Jyoji Yoshizawa, Yoshifusa Abe

Institution: SHOWA Medical University Koto Toyosu Hospital

Language: English

Topic: Kawasaki Disease and Coronary Complications

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,600