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A Comparative Study of Intravenous Ondansetron and Pericardium 6 Acupressure Point Stimulation for the Reduction of Postoperative Nausea and Vomiting

Year: 2025
Type: article
Abstract: OBJECTIVES: The objective of this study was to compare the efficacy of ondansetron and acupressure at pericardium 6 (PC6 or Neiguan) points in managing postoperative nausea and vomiting (PONV). METHODOLOGY: This observational study was conducted in the Department of Orthopedics at Prime Hospital, Dubai, UAE, between 2019 and 2020. Data collection comprised two main components. The first involved recording demographic details, including patients' age, gender, and education level. The second component assessed the severity of nausea and vomiting using a validated visual analog scale (VAS), ranging from 0 to 10, where 0 indicates no nausea, 1-3 represent mild nausea, 4-7 indicat moderate nausea, and 8-10 reflect severe nausea. Symptom severity and frequency were documented at one, three, and seven hours postoperatively. RESULTS: The mean age of the acupressure group (Group A) was 38.92 ± 12.11 years, while that of the ondansetron group (Group B) was 35.91 ± 12.7 years. A statistically significant difference was observed between the groups regarding nausea severity and episode frequency; however, no significant difference was found in vomiting events. Acupressure demonstrated superior effectiveness in reducing both the severity and frequency of postoperative nausea, as well as in minimizing vomiting episodes, compared to ondansetron. CONCLUSION: The findings suggest that acupressure at the PC6 point is more effective than ondansetron in managing PONV, particularly in reducing symptom duration and intensity.
Source: Cureus
DOI: 10.7759/cureus.84664
Language: English
Subfield: Surgery
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4410696244
FWCI:
Cites: 19
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Related to: 10