Work

5q– as the only cytogenetic abnormality in myelodysplastic syndrome with blast excess

Year: 2025

Type: article

Abstract: Cytogenetic studies are required for the diagnosis of myelodysplastic neoplasms (MDS) because the World Health Organization 2022 classification divides MDS into a group with defined genetic abnormalities and MDS that are defined morphologically. Additionally, this paper modifies the terminology to clarify the distinction between MDS with low (5 % in bone marrow) and increased blast cell counts (5–9 % for MDS with blast excess 1 and 10–19 % for MDS with blast excess 2).This article describes the clinical observation of a patient with blast excess MDS and isolated 5q deletion.

Source: Oncohematology

DOI: 10.17650/1818-8346-2025-20-2-75-79

Authors: M. N. Pautova, L. E. Koloskova, A. V. Koloskov, V. N. Marchenko

Institutions: St. Petersburg State Medical Academy "City Hospital No. 26", First Pavlov State Medical University of St. Petersburg

Language: English

Topic: Acute Myeloid Leukemia Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4410698172

FWCI:

Cites: 20

Cited by:

Related to: 10