Work

Vibrio vulnificus Causing Severe Multiorgan Failure in a Patient With Underlying Cirrhosis

Year: 2025

Type: article

Abstract: Vibrio vulnificus is a marine-associated gram-negative bacillus with the potential to cause severe sepsis. V. vulnificus is classically associated with interactions with shellfish, be it due to inoculation of the bacteria via shell laceration or ingestion of raw shellfish. Patients with underlying liver disease are prone to more severe outcomes associated with V. vulnificus infections. In this case, a male patient in his late 30s with chronic alcohol use disorder presented with acute encephalopathy and hematemesis. History revealed ingestion of raw oysters days prior to presentation. After admission, he developed severe multiorgan failure as well as severe persistent thrombocytopenia. He was started on antibiotic therapy with intravenous ceftazidime and oral doxycycline. He underwent partial splenic embolization with improvement in thrombocytopenia and eventual medical stabilization. It is important for clinicians to recognize classic risk factors for V. vulnificus infection to guide timely diagnosis and management.

Source: Cureus

DOI: 10.7759/cureus.84728

Authors: Brandon Y Boeur, Hussein Haidari, Kristen Buchanan, Sagar Kumar, Philip Almalouf

Institutions: University of South Alabama, University of South Alabama Medical Center

Language: English

Topic: Vibrio bacteria research studies

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4410706003