Year: 2025
Type: article
Study design: Case Report
Abstract: Breast carcinoma is a heterogeneous malignancy with multifactorial etiology involving genetic, hormonal, environmental, and reproductive factors. Nulliparity is a recognized risk factor due to prolonged exposure to unopposed endogenous estrogens. This case report presents a 42-year-old nulliparous female diagnosed with right-sided breast carcinoma, who presented with a palpable breast mass and ipsilateral axillary lymphadenopathy. Clinical examination and imaging revealed a well-defined, mobile lesion in the upper inner quadrant of the right breast, classified as BIRADS III. Given the tumor size and nodal involvement, a Modified Radical Mastectomy (MRM) was performed under general anesthesia. Histopathological and receptor status evaluation will guide further management, including adjuvant therapies. This case underscores the importance of recognizing nulliparity as a significant risk factor and highlights the need for individualized, multidisciplinary management strategies in breast cancer. Keywords: Nulliparity, Breast cancer, Mastectomy, Hormone exposure
Authors: B. Suchithra, M. Madhuri, P. Santhoshimatha, K. Vamshi Krishna
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4410711586