Coronary inflammation and atherosclerosis by CCTA in young adults (aged 18-45)
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Peri-coronary adipose tissue attenuation (PCAT), a marker of coronary inflammation, is linked to coronary artery disease (CAD), but data on the role of PCAT in young individuals are limited. Aims: This study explores the interplay of PCAT and CAD by CCTA, in a symptomatic young cohort. Methods and Results: = 0.027). Conclusion: Coronary inflammation is associated with CAD in young patients, independently of traditional risk factors, even among patients with CAC=0 score. These findings highlight its potential as an early marker for guiding preventive strategies.
Authors: Annalisa Filtz, Daniel Lorenzatti, Henry A Dwaah, Carlos Espiche, Santiago F Galgani, Jake T Gilman, Alexandrina Danilov, Andrea Scotti, Piotr J Slomka, Daniel S Berman, Salim S Virani, Mario J Garcia, Khurram Nasir, Leslee J. Shaw, Ron Blankstein, Michael D Shapiro, Damini Dey, Leandro Slipczuk
Institutions: Albert Einstein College of Medicine, Montefiore Health System, Cedars-Sinai Medical Center, Aga Khan University, Baylor College of Medicine, Houston Methodist, Icahn School of Medicine at Mount Sinai, Brigham and Women's Hospital, Wake Forest University Health Sciences, Wake Forest University
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,900
OpenAlex ID: W4410712065