Work

Mesoscale regulation of microtubule-organizing centers by the E3 ligase TRIM37

Year: 2025

Type: article

Source: Nature Structural & Molecular Biology

DOI: 10.1038/s41594-025-01540-6

Authors: Zhong Y. Yeow, Sonia Sarju, Fang-Chi Chang, Lance Y. Xu, Mark van Breugel, Andrew J. Holland

Institutions: Johns Hopkins University, Johns Hopkins Medicine, Queen Mary University of London

Language: English

Topic: Microtubule and mitosis dynamics

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences

Awards: Molecular mechanism that suppresses the proliferation of cells with supernumerary centrioles, Centrosome biogenesis and copy number control, The role of TRIM37 in driving tumorigenesis and cancer-specific vulnerability to PLK4 inhibition

OpenAlex ID: W4410717841

FWCI: 1.998

Cites: 66

Cited by: 4

Related to: 10