Work

Failure of Low-Dose Systemic Corticosteroid in Preventing Acute Exacerbation of Human Leukocyte Antigen B27-Associated Anterior Uveitis: a Case Report

Year: 2025

Type: article

Abstract: This case highlights the progression of human leukocyte antigen B27-associated anterior uveitis to panuveitis despite treatment with low-dose systemic corticosteroids. The patient initially experienced slow disease progression with topical steroid therapy, but the condition deteriorated upon the initiation of 20 mg systemic corticosteroids, marked by the development of a cyclitic membrane preventing vitreous assessment. Increasing the systemic steroid dose to 60 mg led to gradual clinical improvement. This case highlights the inadequate immunosuppression with low-dose steroids in severe uveitis and underscores the importance of timely dose escalation to prevent further complications and ensure favorable outcomes.

Source: Gyemyeong uidae haksulji

DOI: 10.46308/kmj.2024.00150

Authors: You Hyun Lee, Yu Cheol Kim

Institution: Keimyung University

Language: English

Topic: Ocular Diseases and Behçet’s Syndrome

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4410734432