Work

Focal Cortical Dysplasia in an Infant With Aplasia Cutis Congenita: A Case Report

Year: 2025

Type: article

Abstract: Aplasia cutis congenita (ACC) is a rare congenital anomaly characterized by a localized absence of skin, most often affecting the scalp. Although often isolated and with a favorable prognosis, it can be associated with other anomalies, including central nervous system malformations. Cortical dysplasia represents a group of disorders caused by abnormal neuronal migration and organization and is a known risk factor for epilepsy. We report the case of a 10-month-old infant with an occipital ACC lesion present since birth. The infant underwent neuroimaging, which revealed a focal area of cortical dysplasia in the right fronto-opercular/insular region. This case highlights the importance of recognizing associated anomalies in patients with ACC and long-term follow-up in the presence of coexisting neuroimaging abnormalities.

Source: Cureus

DOI: 10.7759/cureus.84842

Authors: Inês Mazeda, Inês Vivas, Sandra Ramos

Institution: Unidade Local de Saúde da Póvoa de Varzim/Vila do Conde

Language: English

Topic: Fetal and Pediatric Neurological Disorders

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4410739656