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Phytochemical Analysis and Antioxidant Activity Assessment of Croton linearifolius Stem Extracts

Year: 2025

Type: article

Abstract: Croton linearifolius is a species with promising medicinal potential. This study investigated the antioxidant activity, total phenolic and flavonoid contents, and conducted chemical prospecting of its ethanolic stem extract and fractions. The extract was obtained by exhaustive percolation with 70% hydroethanolic solution, followed by liquid-liquid partitioning using hexane, dichloromethane, and ethyl acetate. In vitro tests were used for chemical analysis, and antioxidant activity was evaluated by DPPH and FRAP methods. The ethyl acetate fraction showed the highest antioxidant activity (80.62% in DPPH), with elevated phenolic and flavonoid levels, indicating potential for herbal medicine development.

Source: Semina Ciências Exatas e Tecnológicas

DOI: 10.5433/1679-0375.2025.v46.50875

Authors: Cleia Teixeira Santos de Franca, Marcel Mark da Silva Passos, Matheus Andrade Rocha Costa, Esaul Lucas Oliveira, Simone Andrade Gualberto

Institutions: Southwest Bahia State University, Universidade Federal de Catalão, Universidade Federal de Pernambuco

Language: English

Topic: Medicinal Plant Research

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

Open Access status: diamond

Funders: Conselho Nacional de Desenvolvimento Científico e Tecnológico, Universidade Estadual do Sudoeste da Bahia

OpenAlex ID: W4410739835

FWCI:

Cites: 27

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Related to: 10