Work

A fluorescent composite of europium metal organic framework with carbon dots for highly sensitive and specific detection of ciprofloxacin

Year: 2025

Type: article

Abstract: ABSTRACT The excessive and non-judicious use of antibiotics contributes to the majority of pharmaceutical contaminants, leading to negative influence on the environment and human health. Therefore, it is crucial to develop detection techniques for antibiotic contamination that can produce a rapid, sensitive, and antibiotic-selective responses in diverse samples. In this study, a novel composite of europium-based MOFs and red emissive carbon dots (RCDs) was synthesized for sensitive and selective fluorometric sensing of ciprofloxacin (CIP). The RCDs@Eu-BTE composite was characterized using different microscopic and spectroscopic studies. Notably, the composite demonstrated intense fluorescence emission as compared to Eu-BTE and RCDs alone. The enhanced fluorescence of RCDs@Eu-BTE composite resulted in greater sensitivity towards CIP with a limit of detection (LOD) of 0.13 µg/L over a wide linear detection range (0.1-100 µg/L). Moreover, the prepared RCDs@Eu-BTE composite displayed good stability, easy regeneration, and efficient reusability; these features suggest its potential as an effective fluorescence probe for analytical applications.

Source: Talanta Open

DOI: 10.1016/j.talo.2025.100490

Authors: Chetna Sharma, Prakriti Sharda, Neha Bhardwaj, Vanish Kumar, Jyotsana Mehta

Institutions: Thapar Institute of Engineering & Technology, BRIC-National Agri-Food and Biomanufacturing Institute

Language: English

Topic: Carbon and Quantum Dots Applications

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $2,190

Funders: Thapar Institute of Engineering and Technology, National Agri-Food Biotechnology Institute