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An intriguing instance of type 2 lepra reaction-induced granulomatous rhinosinusitis: a case report

Year: 2025

Type: article

Abstract: Hansen disease, or leprosy, is a granulomatous disease caused by the bacteria Mycobacterium leprae, which is endemic worldwide. The upper respiratory tract is the main portal of entry for bacilli, and the paranasal sinuses serve as a reservoir of infection and may exhibit features of rhinosinusitis. We presented a man who manifested features of acute rhinosinusitis not respond to standard therapies incidentally found to have type II lepra reaction and showed miraculous recovery of symptoms following oral steroids and patient on close follow-up. Although leprosy has been declared eliminated globally in most countries, otorhinolaryngologists should still consider type II lepra reactions a differential diagnosis whenever a patient presents with nasal symptoms that do not respond to standard therapies.

Source: International Journal of Otorhinolaryngology and Head and Neck Surgery

DOI: 10.18203/issn.2454-5929.ijohns20251524

Authors: Surya Rajan, Srivalli Chilakamarri, Satish Kumar Chockalingam, Kumaran Ramesh Colbert

Institution: Indira Gandhi Medical College and Research Institute

Language: English

Topic: Leprosy Research and Treatment

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4410768274

FWCI:

Cites: 12

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Related to: 10