Work

Cutaneous pathergy and squamous cell carcinoma: a report of two cases

Year: 2025

Type: article

Abstract: Cutaneous pathergy is a phenomenon demonstrating an exaggerated wound response following minor trauma.While often associated with inflammatory conditions, its association with carcinogenesis is less often described.Recognition of this important phenomenon may be challenging to clinicians who do not encounter it regularly.Cutaneous pathergic squamous cell carcinomas (SCCs) most typically occur as numerous eruptive neoplasms in female patients in sites of trauma or in the background of lichen simplex chronicus or lichenoid dermatoses.Management can be difficult and is typically non-surgical.Herein, we describe two cases of pathergic SCCs and our approach to treatment.

Source: Portuguese Journal of Dermatology and Venereology

DOI: 10.24875/pjdv.25000013

Authors: Armand B. Cognetta Jr., Austinn C. Miller, Chinmoy Bhate, Julianna Gregor, Monica Constantinescu

Institutions: University of Central Florida, Dermatology Associates of Tallahassee, Florida State University

Language: English

Topic: Nonmelanoma Skin Cancer Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: HCA Healthcare