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Isolated testicular metastasis from prostate cancer following three years of hormone therapy and radiotherapy

Year: 2025

Type: article

Abstract: This case report presents a 61-year-old male patient diagnosed with high-risk prostate cancer who underwent hormone therapy and radiotherapy. Three years after beginning treatment, rising prostate-specific antigen (PSA) levels led to a PET CT scan, which identified isolated metastases in the left testicle. The patient then underwent a radical orchiectomy. One-year follow up revealed undetectable PSA and no evidence of any metastases. The significance of this case lies in the uncommon occurrence of testicular metastasis from prostate cancer, particularly when presenting in isolation after a prolonged period following hormone therapy and radiotherapy.

Source: Urology Case Reports

DOI: 10.1016/j.eucr.2025.103080

Authors: Ali Tabibi, Mohammad Sajjad Zabihi, Mahyar Najarian, Mehdi Dadpour

Institutions: Shahid Beheshti University, Shahid Beheshti University of Medical Sciences

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,160