Design, Synthesis and Evaluation of Novel Triphenyl Imidazole Derivatives Through In silico Studies
Year: 2025
Type: article
Abstract: This study focuses on the design, synthesis and insilico analysis of novel Triphenyl imidazole derivatives.Debus-Radiziszewski imidazole synthesis is a simple and highly efficient method for synthesis of 2, 4, 5 -triphenyl imidazoles derivatives.Microwave assisted synthesis has emerged as a new lead in organic synthesis which makes the synthetic chemistry easy and effective.The structural integrity of the synthesized compounds was confirmed via comprehensive spectroscopic techniques, including Infrared Spectroscopy (IR).Molecular docking is studied to predict the binding affinity of ligands to receptor proteins.These findings not only validate the successful synthesis of the Triphenyl imidazole derivatives but also highlight their potential for further drug development.
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4410778686