Year: 2025
Type: article
Abstract: A chronic, systemic inflammatory disease that mostly affects synovial joints, rheumatoid arthritis (RA) causes gradual joint degeneration, deformity, and disability. Systemic symptoms, autoantibody production, and chronic synovial inflammation are its defining characteristics. Its development and progression are influenced by immunological, environmental, and genetic variables, albeit the precise aetiology is yet unclear. Millions of people are impacted by the illness globally, particularly women, and it has a major negative influence on quality of life. Results have improved with early diagnosis and vigorous therapy with biologics and disease-modifying anti rheumatic medications (DMARDs). However, there are still issues with managing extraarticular problems, personalised therapy, and illness prognosis. Future improvements in illness management and perhaps remission are possible with ongoing research into immunological mechanisms and targeted medicines.
Author: Mr. Shubham Mahajan
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4410780662