Antioxidant efficacy of synthesized composite copper lutein nano nutraceuticals from brassica oleracea var italica
Year: 2025
Type: article
Abstract: Aim: Due to its antioxidant properties, lutein scavenges reactive oxygen species, including lipid peroxy radicals and singlet oxygen. Despite the therapeutic promise derived from its various physiological functions, lutein's absorption and stability issues make efficient distribution challenging. Nanotechnology applications in pharmaceuticals have been the subject in recent decades. Similar to nanopharmaceuticals, a new class of nanomaterials known as nanonutraceuticals has evolved due to the application of nanotechnology for improved nutraceutical delivery. Methods: For green synthesis, B. oleracea stalks and florets were utilized individually in a copper sulphate solution. The synthesized Copper nanoparticles were characterized and screened for their antibacterial and anti-biofilm activities. Results: At 400μg/ml concentrations, FLNP and FNP demonstrated 92 and 88% DPPH free radical scavenging, respectively. Comparing the different NPs to the positive control, FLNP demonstrated the highest H2O2 scavenging activity (IC50 72.55μg/ml), followed by FNP. When compared to the positive control, FLNP, FNP, and Lutein demonstrated antioxidant capacities of 94, 91, and 87% at 400µg/ml using the reducing power method. According to our ferrozine assay results, FLNP demonstrated an efficient ability to bind iron, suggesting that this property may be linked to its antioxidant properties. According to their different antioxidant capacities, FLNP and FNP demonstrated 92 and 88% FZ reduction ability. Conclusion: The present study was successful in synthesizing composite lutein-based copper nanoparticles and also confirmed of the potential antioxidant activity exhibited by the composite particles. The composite particles did exhibit enhanced antioxidant activity when compared to other controls.
DOI: 10.14419/fwg9s764
Institution: Mangalore University
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4410780688