Multidisciplinary Team Intervention: Catalysts for Changing Prognosis in Advanced Breast Cancer
Year: 2025
Type: article
Study design: Observational Study
Abstract: PURPOSE: Multidisciplinary team (MDT) discussions are standard in cancer care; however, their effect on advanced breast cancer (ABC) prognosis is not well-documented. This study examined the impact of MDT intervention on ABC patient survival. METHODS: A retrospective analysis of ABC patients diagnosed 2018 to 2021 was conducted by dividing them into MDT and non-MDT groups. Kaplan-Meier analysis was used to compare progression-free survival (PFS) and overall survival (OS) between the groups. Prognostic factors were evaluated using multivariate Cox regression analysis with subgroup analysis and 1:1 propensity score matching (PSM) to control for confounders. RESULTS: = 0.121). CONCLUSION: MDT effectively controlled the disease progression and improved OS in specific patient subgroups.
Source: Journal of Breast Cancer
Authors: Jun-Sheng Zheng, Hui Fu, Zhao Bi, Zhi-Qiang Shi, Jin-Ming Yu, Peng-Fei Qiu, Yong-Sheng Wang
Institutions: Shandong Tumor Hospital, Shandong First Medical University
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $500
Awards: G2162560179, G6103330382
OpenAlex ID: W4410796374