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A phase 2 study of the OX40 agonist BGB-A445, in combination with docetaxel or BGB-15025, an HPK1 inhibitor, in patients with NSCLC pretreated by anti-PD-(L)1 antibodies.

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Year: 2025
Type: article
Study design: Clinical Trial
Source: Journal of Clinical Oncology
DOI: 10.1200/jco.2025.43.16_suppl.e14513
Authors: Tae Min Kim, Haiyan Liu, Byoung Chul Cho, Youngjoo Lee, Byoung Yong Shim, Fang Ma, Mingjuan Zhang, Jianchun Duan, Hongling Li, Ramil Abdrashitov, Zhaoyin Zhu, Hugh Giovinazzo, Ye Zhao, Yajie Guo, Jie Wang
Institutions: Seoul National University Hospital, Shandong First Medical University, Yonsei University, Yonsei University Health System, Yonsei Cancer Hospital, National Cancer Center, The Catholic University of Korea St. Vincent's Hospital, Second Xiangya Hospital of Central South University, Weihai Municipal Hospital, Shanxi Provincial Cancer Hospital, Gansu Provincial Hospital, BeOne Medicines (Switzerland), Chinese Academy of Medical Sciences & Peking Union Medical College, Cancer Hospital of Chinese Academy of Medical Sciences
Language: English

Topic: Cancer Immunotherapy and Biomarkers
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funder: BeiGene
OpenAlex ID: W4410804577
FWCI: 0.371
Cites:
Cited by: 1
Related to: 10
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