11th European Stroke Organisation Conference Abstracts – 21-23 May 2025, Helsinki, Finland
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background and Aims: Artery of Percheron stroke (AOPS) is a rare infarction subtype bilaterally affecting the paramedian thalami. Owing to its rarity and atypical presentation, AOPS is often challenging to diagnose and manage with an uncertain long-term outcome. Methods: We assessed clinical and radiological data of AOPS from six centers in Switzerland, Lithuania and Latvia between 2003-2023. Patients were eligible if they were admitted within 72 hours of onset, with AOPS confirmed by CT/MRI. Results: We identified 90 AOPS cases (mean age 67.8±15.2 years, 43.3%female). A wake-up stroke was present in 32%, and median time to ED was 151 minutes (IQR 72–722). Main symptoms included decreased consciousness (79%), anterograde amnesia (68%), corticospinal signs (64.7%),aphasia (42.7%), gaze palsy (34.9%), and confusion/inattention (33.7%).Stroke diagnosis was delayed in 20.3%; none of these missed cases under-went MRI as first neuroimaging, whereas 22.2% of the non-missed group did undergo MRI. Acute stenosis/occlusion or hypoperfusion were observed in 27.9%, and 15 (25.9%) received revascularization therapy (10thrombolysis, one thrombectomy, four bridging). Poor outcomes (mRS3–6) at three months occurred in 58.3% of missed and 54% of non-missed cases, versus 50% among those revascularized. Conclusion: In this large multicenter AOPS cohort, MRI as first-line imaging in atypical stroke presentations may help recognition. Revascularization therapy may offer better outcomes, underscoring the need for improved diagnostic strategies. Ongoing analyses focus on acute and neuro-psychological/psychiatric outcomes and comparisons with anterior circulation strokes.
Source: European Stroke Journal
Authors: Daskeviciute, Aurelija, Korv, Janika, Jurjans, Kirstaps, Matijošaitis, Vaidas, Vaitkus, Antanas, Teivane, Agnete, Grosmane, Arta, Miglane, Evija, Jatužis, Dalius, Zaboras, Edgaras, Šumskienė, Vitalija, Samarüütel, Inga, Gross-Paju, Katrin, Sikk, Katrin, Vilionskis, Aleksandras, Masiliūnas, Rytis
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $4,400
OpenAlex ID: W4410805995