Development of New Indole-Based N-Heterocyclic Carbene Copper Complexes and Their Applications in Catalysis
Year: 2025
Type: article
Abstract: High Resolution Image Download MS PowerPoint Slide This study disclosed the synthesis and characterization of a series of copper N -heterocyclic carbene (NHC) complexes incorporating an indole skeleton. Among these complexes, the Cu-NHC complex with a p -methoxyphenyl group on the indole ring exhibited stability in air for up to six months. In contrast, Cu-NHC complexes bearing alkyl groups on the indole ring were stable under a nitrogen atmosphere for one month. These newly developed Cu-NHC complexes proved effective as catalysts for hydrosilylation of carbonyls in 0.5 mol % loading and N -arylation of oxazolidinones and amides with aryl iodides in 8 mol % loading.
Source: The Journal of Organic Chemistry
Authors: Chun-Fa Lin, Ya-Hsuan Tseng, Hui-Yu Hsieh, Pei-Jei Hung, Yan-Wen Huang, Dong-Sheng Lee, Ta-Jung Lu
Institution: National Chung Hsing University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $4,500
Funder: Ministry of Education
OpenAlex ID: W4410807938