Work

Using single-cell transcriptomics to reveal CD226 upregulation and enhancement of CD19-CAR-T function in the inhibitory CNS microenvironment of refractory CNS lymphoma.

Year: 2025

Type: conference-abstract

Source: Journal of Clinical Oncology

DOI: 10.1200/jco.2025.43.16_suppl.2020

Authors: Ulrike Gerdemann, James Kaminski, Alexandre Albanese, Isabella Schichter, Paula Keskula, Ryan A. Fleming, Fran Alvarez-Calderon, Lorenzo Cagnin, Jillian Zavistaski, Austin Moore, Soumya Poddar, Ugonma Nnenna Chukwueke, Lea Steinberg, Michael Mattie, Caroline Falvey, Riemke Bouvier, Alexandra Torres, Caron Jacobson, Lakshmi Nayak, Leslie Kean

Institutions: Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston Children's Hospital, Kite Pharma (United States), Dana-Farber Cancer Institute

Language: English

Topic: CAR-T cell therapy research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4410818398

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Related to: 10