Synthesis and characterization of diallylic polysulfanes and study toward the synthesis of thiarubrine E
Year: 2011
Type: dissertation
Abstract: Garlic oil contains diallyl polysulfanes as major components, which have been used as environmentally benign bird repellants and nematicides. While previous studies found that the biological activity of polysulfanes increases with numbers of sulfur atoms, higher diallyl polysulfanes are currently unavailable. A simple approach was developed, using liquid sulfur as a reagent, to the synthesis of diallyl polysulfanes containing chains of more than 20 sulfur atoms. This method was successfully applied to other diallylic disulfides and to garlic oil to give new families of polysulfanes. Some diallyl polysulfanes were isolated in a pure form by preparative high performance liquid chromatography (HPLC) and characterized by nuclear magnetic resonance (NMR) spectroscopy. Those synthesized families of diallyl polysulfanes and garlic oil were also characterized by ultra performance liquid chromatography- (Ag+)-coordination ion spray-mass spectrometry (UPLC-Ag+-CIS-MS), and new members of families of silver-chelators were found in garlic oil.
DOI: 10.54014/2923-z3mm
Author: Wang, Kai
Institution: University at Albany, State University of New York
Language: English
Topic: Garlic and Onion Studies
Subfield: Plant Science
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4410822062