Work

Molecular blueprint of a cellular sorting centre

Year: 2025

Type: article

Abstract: Endosomes are sorting centres inside cells that decide where to deliver materials that are taken from outside or from other parts of the cell. A comprehensive map of endosomal proteins uncovers new components, and reveals the assembly and architecture of hundreds of molecular machines that work together in the endosomal system. Experimental techniques and the AI tool AlphaFold are used to generate a comprehensive map of early endosomal proteins and their interactions.

Source: Nature

DOI: 10.1038/d41586-025-01564-4

Language: English

Topic: Cellular transport and secretion

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $12,690

OpenAlex ID: W4410823906

FWCI:

Cites: 4

Cited by:

Related to: 10