Year: 2025
Type: article
Study design: Case Report
Abstract: Rotavirus infection is a common cause of pediatric gastroenteritis, often self-limited but occasionally associated with extraintestinal complications. This report describes a 12-year-old vaccinated girl who presented with acute gastroenteritis and an incidental elevation of serum creatine kinase (CK). Despite the absence of muscle pain or weakness during hospitalization, laboratory findings indicated skeletal muscle involvement, with elevated CK and aldolase levels, and a predominance of CK-MM isoenzyme. Myocardial involvement and rhabdomyolysis were ruled out. The patient recovered with supportive care, and CK levels normalized after discharge, although she reported mild post-discharge fatigue. Rotavirus-associated myositis is rare and likely underrecognized, particularly in young children who may not verbalize muscle symptoms. This case highlights the importance of considering myositis in patients with elevated CK during rotavirus infection, even in the absence of overt muscular symptoms.
Source: Cureus
DOI: 10.7759/cureus.84946
Authors: Arisa Hayashi, Mika Ukai, Shoichiro Kanda, Keiichi Takizawa, Akiko Kinumaki
Institution: The University of Tokyo
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4410828105