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Demyelinating Sarcoid Polyneuropathy With Reversible Conduction Block: A Case‐Report

Year: 2025

Type: article

Abstract: ABSTRACT The pathomechanism of sarcoid polyneuropathy remains unknown though different hypotheses are discussed. A 57‐year‐old female patient presented with painful paresthesia and progressive weakness of the lower extremities. Intravenous immune globulin therapy for presumed chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) failed to control disease activity. Glucocorticoid pulse therapy was associated with rapid improvement of the neurological symptoms and resolved the conduction block, which indicates inflammatory processes involved in sarcoid polyneuropathy pathogenesis.

Source: Neurology and Clinical Neuroscience

DOI: 10.1111/ncn3.70024

Authors: Stanislav Svergun, Vasilieios‐Periklis Stamatellos, Almut Barthel, Gunnar Ulm, Nikolas Ruffer, Werner Stenzel, Robert Stingele

Institutions: DRK Kliniken Berlin, University Medical Center Hamburg-Eppendorf, Humboldt-Universität zu Berlin, Freie Universität Berlin, Charité - Universitätsmedizin Berlin

Language: English

Topic: Peripheral Neuropathies and Disorders

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4410830449

FWCI:

Cites: 5

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Related to: 10