Clinical Efficacy of Microecological Modulator Combined with Phototherapy in Elderly Diabetic Vulvovaginitis Based on Multi-Dimensional Nursing Intervention
Year: 2025
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: 目的：通过观察微生态调节剂联合红光疗基于多维度护理干预治疗老年糖尿病外阴阴道炎临床疗效，并探讨其机制。方法：本研究选取2024年4月2025年4月入住延安市安塞区人民医院与安塞区妇幼保健院妇产科或内科的老年糖尿病合并外阴阴道炎患者作为研究对象。采用随机双盲对照试验(RCT)，分2组(n = 32/组)：观察组：微生态调节剂 + 光疗 + 多维度护理；对照组：传统药物治疗(甲硝唑/克霉唑) + 常规护理。收集治疗2周后症状评分(瘙痒、灼痛VAS评分)、复发率(治疗后1、3个月随访)数据。计数资料描述用频数与构成比((n) %)，两组外阴阴道炎患者复发率组间比较采用χ2检验；治疗2周后症状评分符合正态分布采用( X ¯ ±s )描述，两组患者组间比较采用t检验，非正态分布的计量资料使用中位数、四分位数M (P25, P75)表示，两组患者组间比较采用非参数检验；以P P P > 0.05)。微生态调节剂联合光疗基于多维度护理干预治疗方案在治疗1、3个月后复发率显著低于对照组，差异具有统计学意义(P Objective: To observe the clinical efficacy of microecological regulator combined with red light therapy in the treatment of elderly diabetic vulvovaginitis based on multi-dimensional nursing intervention, and to explore its mechanism. Methods: Elderly patients with diabetes mellitus and vulvovaginitis who were admitted to the obstetrics and gynecology department or the internal medicine department of Ansai County People’s Hospital of Yan’an City from April 2024 to April 2025 were selected as the study objects. A randomized double-blind controlled trial (RCT) was conducted and divided into 2 groups (n = 32/group): Observation group: microecological regulator + phototherapy + multi-dimensional nursing; Control group: traditional drug therapy (metronidazole/clotrimazole) + conventional nursing. Symptom score (VAS score of pruritus and burning pain) and recurrence rate (follow-up 1 and 3 months after treatment) were collected after 2 weeks of treatment. Frequency and component ratio ((n) %) were used to describe the counting data. The inter-group comparison of the recurrence rate of vulvovaginitis patients between the two groups was conducted by χ2 test. After 2 weeks of treatment, symptom scores consistent with normal distribution were described by ( X ¯ ±s ). Comparison between the two groups was performed by T-test; measurement data with non-normal distribution were represented by median and quartile M (P25, P75), and comparison between the two groups was performed by non-parametric test. P P P > 0.05). The recurrence rate of microecological regulator combined with phototherapy based on multi-dimensional nursing intervention regimen was significantly lower than that of control group after 1 and 3 months of treatment, the difference was statistically significant (P < 0.05). Conclusion: The combination therapy of microecological regulator and red light therapy based on multi-dimensional nursing intervention is significantly better than single drug therapy in symptom relief (pruritus, abnormal secretion) and recurrence rate. This combination program provides a safer and durable treatment strategy for elderly diabetic vulvovaginitis through the multi-target intervention mode of “local treatment + systemic management” and embodies the comprehensive benefit of comprehensive treatment.
Source: Advances in Clinical Medicine
Author: 慧慧 赵
Language: English
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4410833324