Work

[Effects of donor T cell stat3 deficiency on acute intestinal graft-versus-host disease in mice].

Year: 2025

Type: other

Abstract: Knocking out Stat3 in graft T cells reduces T cell damage to intestinal stem cells, thereby ultimately alleviating GI-aGVHD while maintaining a stable GVL effect.

Source: PubMed

DOI: 10.3760/cma.j.cn121090-20250107-00011

Authors: Y X Xu, X Q Wang, S J Yang, Q X Song, J Wei, X Zhang

Institutions: Army Medical University, Affiliated Hospital of North Sichuan Medical College, Xinqiao Hospital, Jinfeng Laboratory

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Natural Science Foundation of China, Natural Science Foundation of Chongqing

Awards: G3946343723, G4149890223, G6865402964, G7211153835

OpenAlex ID: W4410840935

Cites:

Cited by:

Related to: 10