Work

Discovery of highly potent naphthalene/quinoline-based PAD inhibitors: Structure-activity relationship, selectivity, and cytotoxicity

Year: 2025

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2025.117830

Authors: Yijiang Jia, Sina Bahraminejad, Xin Duan, Sydney Kong, Ayijiang Taledaohan, Chenyao Jiang, Dejian Ma, Jianxiong Jiang, Yuji Wang, Jiawang Liu

Institutions: University of Tennessee Health Science Center, University of Tsukuba, Vanderbilt University, Capital Medical University

Language: English

Topic: Heterocyclic Compound Synthesis and Bioactivity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, Health Science Center, University of Tennessee, National Institute on Aging, National Institute of Neurological Disorders and Stroke, National Center for Research Resources

Awards: EP2 Antagonists for Ischemic Stroke, G6493600551, Acquisition of a Q-TOF Mass Spectrometer, Acquisition of a 400MHz Solution NMR System with an Autosampler, Mass Spectrometer for Small Molecule Drug Development, Trans-omics Integration of Multi-omics Studies for Osteoporosis

OpenAlex ID: W4410857431

FWCI: 1.697

Cites: 24

Cited by: 6

Related to: 10