Work

Neural and Psychological Mechanisms Linking Romantic Breakups to Major Depressive Disorder: A Neurobiological Perspective

Year: 2025

Type: article

Abstract: Romantic breakups can have profound psychological and neurological effects, often leading to the development or exacerbation of Major Depressive Disorder (MDD). This paper explores the neural and psychological mechanisms underlying the relationship between romantic breakups and MDD. It examines the roles of brain regions such as the prefrontal cortex, amygdala, and nucleus accumbens, as well as neurotransmitters like serotonin, dopamine, and cortisol. Psychological factors including attachment styles, rumination, and emotional dysregulation are also discussed. Understanding these mechanisms can inform therapeutic interventions aimed at mitigating post-breakup depression. Keywords: Romantic breakup, Major Depressive Disorder, neurobiology, emotional regulation, attachment styles, neurotransmitters, cognitive flexibility.

Source: Shodh Manjusha An International Multidisciplinary Journal

DOI: 10.70388/sm240124

Author: Sandeep Kumar

Institution: NIILM University

Language: English

Topic: Attachment and Relationship Dynamics

Subfield: Social Psychology

Field: Psychology

Domain: Social Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4410864287