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Polymorphic Ventricular Tachycardia (PMVT) in a Patient With Troponin-Negative Chest Pain: A Case Report and Literature Review

Year: 2025

Type: article

Abstract: Polymorphic ventricular tachycardia (PMVT) is a potentially life-threatening arrhythmia, typically associated with acute myocardial ischemia or inherited channelopathies. We present a case of PMVT in the context of critical coronary artery disease (CAD) but without biomarker-evident myocardial injury, such as troponin elevation. We present a case of a 61-year-old man with critical left anterior descending (LAD) artery stenosis who developed symptomatic PMVT. This case highlights the paradox of negative troponin values despite severe coronary pathology and a life-threatening arrhythmia. Despite initial normal troponin levels, the patient's recurrent chest pain and arrhythmias were ultimately attributed to critical LAD stenosis, which was successfully treated with percutaneous coronary intervention (PCI). This case emphasizes the importance of considering high-risk coronary disease, particularly in patients with exertional symptoms and arrhythmias, even when initial biomarkers may be reassuring. It underscores the importance of considering ischemia even when troponin levels are normal, particularly in patients with unstable angina. The case illustrates the limitations of relying solely on troponin for risk stratification in acute coronary presentations and supports the need for comprehensive clinical and electrocardiographic evaluation.

Source: Cureus

DOI: 10.7759/cureus.85016

Authors: Abhimanyu Baruah Baruah, Weje Chituru, Chin Soo, Syed Mustafa, Adnan Ahmed, Jhiamluka Solano