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ROCK-dependent mechanotransduction of macroscale forces drives fibrosis in degenerative spinal disease

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Year: 2025
Type: article
Source: Nature Biomedical Engineering
DOI: 10.1038/s41551-025-01396-7
Authors: Muhamed Hadzipasic, Margaret S. Sten, Elie Massaad, Ali Kiapour, Ian D. Connolly, Eric Esposito, Ryan Burns, George Nageeb, Muneeb A. Sharif, Joseph Bradley, Leland Richardson, Sami Shaikh, Bryan D. Choi, Gunnlaugur P. Nielsen, Jean-Valery C. Coumans, Lawrence F. Borges, John H. Shin, Alan J. Grodzinsky, Hadi T. Nia, Ganesh M. Shankar
Institutions: Boston University, Harvard University, Massachusetts General Hospital, Massachusetts Institute of Technology
Language: English

Topic: Spine and Intervertebral Disc Pathology
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funder: North American Spine Society
OpenAlex ID: W4410865239
FWCI: 3.589
Cites: 52
Cited by: 6
Related to: 10
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