Work

Decarboxylative sulfation by persulfates

Year: 2025

Type: article

Abstract: Decarboxylative radical sulfation is achieved with persulfates functioning as both oxidants and sulfating agents to facilitate C–OSO 3 − bond formation. Synthesis of organosulfates from carboxylic-acid-based drugs may improve their metabolic profiles.

Source: Chemical Science

DOI: 10.1039/d5sc03129j

Authors: Zhen Xia, Ting Deng, Chunlan Song, Jiakun Li

Institutions: Huaihua University, Hunan University

Language: English

Topic: Sulfur-Based Synthesis Techniques

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: Hunan University, Natural Science Foundation of Hunan Province, Wuhan University

Award: 电化学诱导实现C-O成键硫酸化及其在蛋白质修饰中的应用