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Associative learning by C. elegans is variable when butanone is paired with starvation

Year: 2025
Type: article
Abstract: has been reported to show a reduction in its preference for the odorant butanone after prior exposure to butanone coupled with starvation. Here we report unexplained variability in such associative learning. Pre-exposure of unfed worms to butanone resulted in different responses during different trials of subsequent chemotaxis assays - from strong avoidance to enhanced attraction. Given this variation in associative learning despite the artificially controlled lab setting, we speculate that in dynamic natural environments such learning might be rare and highlight the challenge in discovering evolutionarily selected mechanisms that could underlie learning in the wild.
Source: PubMed
Language: English
Open Access status: green
OpenAlex ID: W4410875841
FWCI: 0.356
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Cited by: 1
Related to: 10