Dietary Protein Intake Recommendations for Patients with Non–Dialysis-Dependent CKD
Year: 2025
Type: article
Abstract: Protein intake is crucial to maintain human health, and an adequate quantity and quality of dietary protein intake (DPI) is particularly important in patients with CKD. Both an insufficient amount of DPI ( i.e ., <0.6 g/kg body weight (body wt)/d) and an excess amount of DPI ( i.e ., >1.3 g/kg body wt/d) pose potential health hazards in patients with CKD stages 3-5. Therefore, to optimize patient outcomes, healthcare providers should be familiar with the effects of both inadequate and excessive DPI in this population. The Kidney Disease Outcome Quality Initiative guidelines on DPI are rooted in detailed analyses of available scientific evidence and provide detailed recommendations regarding different dietary interventions strategies to achieve optimal quantity and quality of DPI. The more recent Kidney Disease Improving Global Outcomes guidelines on CKD management have a substantially broader scope and include a relatively brief section on diet, recommending a DPI of 0.8 g/kg body wt/d, emphasizing the need to avoid a DPI of >1.3 g/kg body wt/d. Besides aiming for a DPI of approximately 0.6-0.8 g/kg body wt/d in patients with CKD stages 3-5, successful practical implementation of dietary interventions requires an individualized approach which considers patient characteristics, such as sociocultural norms, habitual dietary habits, and nutrition literacy as well as systemic factors such as feasibility and availability of interventions.
Institutions: University of Tennessee Health Science Center, Memphis VA Medical Center, University of Trento, Lyon 1 Université, Inserm, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Hospices Civils de Lyon, Laboratoire de recherche en cardiovasculaire, métabolisme, diabétologie et nutrition, Indiana University School of Medicine, University of Genoa, Vanderbilt University, Vanderbilt University Medical Center, University of California, Los Angeles, The Lundquist Institute, Harbor–UCLA Medical Center, Purdue University West Lafayette, Klinikum im Friedrichshain, University of Wollongong, University of California San Diego, Houston Methodist, Weill Cornell Medicine, National University of Singapore, Singapore General Hospital, Duke-NUS Medical School, East Carolina University
Language: English
Subfield: Nephrology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Award: G4628224496
OpenAlex ID: W4410890133