Work

Focal endocardial pulsed-field ablation for the treatment of inappropriate sinus tachycardia: A case report

Year: 2025

Type: article

Abstract: Inappropriate sinus tachycardia (IST) is a diagnosis of exclusion, characterized by debilitating symptoms such as a markedly elevated heart rate at rest or with minimal exertion, along with exercise intolerance. The condition is defined by a resting heart rate exceeding 100 bpm and a mean ambulatory heart rate over 90 bpm without a clear secondary cause. (1) Although the exact pathophysiology remains unclear, IST is believed to be multifactorial, involving abnormal neurohumoral modulation, antibody-mediated processes, and various receptor hyper- or hyposensitivity mechanisms.

Source: HeartRhythm Case Reports

DOI: 10.1016/j.hrcr.2025.05.022

Authors: Mohamed A. Mostafa, Jonathan R. Brock, Edward H. Kincaid, Prashant D. Bhave, S. Patrick Whalen

Institutions: Wake Forest University Health Sciences, Wake Forest University

Language: English

Topic: Cardiac Arrhythmias and Treatments

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,100