Year: 2025
Type: article
Abstract: The phytochemical exploration in medicinal plants is increasingly recognized for its diverse pharmacological benefits. This research aims to evaluate the antioxidant potential and anticancer properties of Eclipta prostrata L. (EPL) extracts on human breast adenocarcinoma (MCF7), hepatocellular carcinoma (HepG2), and human gastric carcinoma (MKN-7) cell lines. The dried plant material was extracted in 70% ethanol, n-hexane, ethyl acetate, and n-butanol solvents. The antioxidative properties of EPL extracts were assessed through ABTS and FRAP assays, while the antiproliferative effects were measured using the sulforhodamine B assay. Findings indicated that the ethyl acetate extract exhibited higher antioxidant and cytotoxic activities against the HepG2 cell line compared to other extracts. Future research should aim to isolate and characterize the specific bioactive compounds responsible for the observed anticancer and antioxidant effects, and clarify their mechanisms of action.
Source: Tạp chí Nghiên cứu Y học
Authors: Phan Hong Minh, Ta Phuong Yen, Tran Thi Hong Ngoc, Le Anh Tuan, Nguyen Thuc Thu Huong, Mai Phuong Thanh
Language: English
Topic: Medicinal Plant Research
Subfield: Plant Science
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4410899840