Analyze the effects of A paniculata leaf extract in methanol on Candida albicans RFG1 gene expression
Year: 2025
Type: article
Abstract: The gene expression studies showed decreased level of Rfg1 gene expression in C. albicans upon treatment with methanolic leaf extracts of A. paniculata. However, similar molecular studies on pure compounds from this plant may give strong evidences about the pharmacological potential of the plant and thus can be formulated as an effective drug for the treatment of infections caused by C. albicans. The bioassays on antifungal activity of the methanolic leaf extract of A. paniculata showed inhibitory effects against human pathogen C. albicans.
Authors: P Sagadevan, M Raghunath, M Nagarajan, M Kannan, N Sribala, Charles Paul, V Senthil kumar, Aruna Devi, P Kavipriya
Language: English
Subfield: Food Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4410904530