Association between sarcopenia on residual back pain after percutaneous kyphoplasty for osteoporotic vertebral compression fractures
Year: 2025
Type: article
Study design: Observational Study
Abstract: OBJECTIVE: This study aimed to investigate whether sarcopenia affects residual back pain (RBP) after percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fractures (OVCF). METHODS: We retrospectively analyzed the clinical data of 231 patients with single-segment OVCF treated with PKP between January 2023 and December 2023. Postoperative RBP was assessed at 1 month using the visual analogue scale (VAS). Patients with a VAS score ≥ 4 were classified as the RBP group, while those with a score < 4 served as controls. Sarcopenia was diagnosed using the skeletal muscle mass index (SMI), calculated by dividing the cross-sectional muscle area at the T12 vertebral level (measured via chest CT) by height squared. Univariate analysis compared clinical and imaging data between groups, and binary logistic regression identified risk factors. RESULT: No significant differences were observed between groups in gender, BMI, surgical segment, hypertension, diabetes, or coronary heart disease (P > 0.05). However, age, BMD, SMI, bone cement usage, and sarcopenia prevalence differed significantly (P < 0.05). Binary logistic regression identified BMD and sarcopenia as independent risk factors for RBP after PKP. CONCLUSION: OVCF patients with sarcopenia have a higher likelihood of postoperative RBP, with an incidence approximately twice that of non-sarcopenic patients. Preoperative sarcopenia screening should be prioritized, and postoperative anti-muscular atrophy therapy actively implemented.
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,090
Awards: G2808385481, G413791825, G6872134681
OpenAlex ID: W4410906108