Study on the potent binding of anti Cancerous Drug Binding using various spectroscopic and computational Techniques
Year: 2025
Type: article
Abstract: An alarming number of people worldwide lose their lives to cancer every year. Anticancer medications are used to treat malignant growths or malignancies in the human body. Because human serum albumin [HSA] is a protein that is present in human blood and has the ability to bind, it is in charge of delivering a variety of medications to the relevant body areas. The purpose of this work is to investigate the binding of HSA to VA-7/VI-9 as an anti-cancer medication. A number of thermodynamics parameters need to be determined. Overall, the binding interaction process's conformational and structural modifications, binding constant, Vander Waal forces, and binding energy were defined in the current work. Numerous computational methods and spectroscopic techniques were employed to bind anti-cancer drugs to HSA. The thermodynamic parameters involved in the binding process are estimated using circular dichroism (CD) and molecular docking.
Author: Neha Neha
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4410918476