Work

Tissue Mechanics and Hedgehog Signaling Crosstalk as a Key Epithelial–Stromal Interplay in Cancer Development (Adv. Sci. 35/2024)

Year: 2024

Type: article

Abstract: Cancer Cells' Mastery of Their Environment Cancer cells actively reshape their surroundings. By releasing sonic hedgehog, they stiffen the extracellular matrix, enlisting stromal cells as allies. This increased stiffness heightens actomyosin cytoskeleton tension, activating oncogenic transcription factors and driving invasive tumor growth. More details can be found in article number 2400063 by Jeongeun Hyun, Hae-Won Kim, and co-workers.

Source: Advanced Science

DOI: 10.1002/advs.202470210

Authors: Shanika Karunasagara, Ali Taghizadeh, Sang‐Hyun Kim, So Jung Kim, Yong‐Jae Kim, Mohsen Taghizadeh, Moon‐Young Kim, Kyu‐Young Oh, Jung‐Hwan Lee, Hye Sung Kim, Jeongeun Hyun, Hae‐Won Kim

Language: English

Topic: Cellular Mechanics and Interactions

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $6,120

OpenAlex ID: W4410922840

FWCI:

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