Work

Molecular Characterization and Antibiogram Studies of Urinary Tract Infection Bacteria Isolated From Urine Samples of Pregnant Women

Year: 2025

Type: article

Abstract: Urinary tract infection is a frequent ailment during pregnancy that creates critical complications for the mother and fetus requiring immediate detection and prevention.In the current study, we aimed to investigate the microbial diversity of microbes associated with urinary tract infection by randomly selecting urine samples from 100 patients exhibiting UTI symptoms.We characterized patients' bacterial isolates by differential culture media, following the identification of an isolate by the 16s rRNA gene.Drug susceptibility testing revealed that Gram-negative bacteria demonstrated higher resistance to the drugs as compared to Gram-positive organisms.Overall, in this study, six isolates were identified as E. coli and designated as the main causative agent of UTIs and diagnosed in the thirdtrimester, which is the most dangerous stage of pregnancy for mothers.Appropriate and receptive antibiotics and therapeutic drugs with no side effects and those that are inexpensive and widely available are needed for the treatment of UTIs.Appropriate use of antibiotics can reduce the complications of infected mothers and fetuses.

Source: Applied Ecology and Environmental Research

DOI: 10.15666/aeer/2303_40834097