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An Insight Into Medicinal Properties of Quinoxaline Scaffold, With a Focus on Their Anticancer Potential as Intercalating Agents

Year: 2024

Type: article

Abstract: The antitumor properties of synthetic heterocyclic compounds are among the most important properties that can be made use in medicinal chemistry. More specifically, their significant cytotoxic effects against many types of human tumor cells, as well as their roles as various topoisomerase inhibitors. In recent years, quinoxaline derivatives have frequently attracted the interest of medicinal chemistry researchers due to their promising anticancer properties. The present study is a review of the latest advances in quinoxaline derivative-related research, with a focus on their anticancer activities as DNA intercalator.

Source: Al-Azhar Journal of Pharmaceutical Sciences/Al-Azhar Journal of Pharmaceutical Sciences

DOI: 10.21608/ajps.2024.429449

Authors: Mohammed A Dahab, Mohammed Abdel Hamid, Ibrahim Eissaa, Mohammed Mohammed

Institution: Al-Azhar University

Language: English

Topic: Synthesis and Biological Evaluation

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4410938543

FWCI: 0.141

Cites:

Cited by: 1

Related to: 10