Figure 4 from First-in-Human Study to Evaluate the Safety and Efficacy of Anti-GDF15 Antibody AZD8853 in Patients with Advanced/Metastatic Solid Tumors
Year: 2025
Type: other
Abstract: Changes in peripheral T cells during AZD8853 treatment. The patient with a strong increase in proliferating T cells (left plots) started with a very low number at baseline (right plots). Whole blood samples were collected at various timepoints for analysis of numbers of peripheral T cells using flow cytometry–based immunophenotyping of circulating lymphocytes. *Baseline is the average of the screening and C1D1 predose (visit day 0). C, cycle; D, day; EOT, end of treatment; Ki67+, antigen Kiel 67 positive.
Language: English
Topic: GDF15 and Related Biomarkers
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4410967516