Work

Decoding leprosy: immune response, clinical manifestations and emerging diagnostic approaches

Year: 2025

Type: article

Abstract: Leprosy is an infectious disease characterized by a broad immunological spectrum, which underlies its diverse clinical presentations and contributes to the physical and emotional disabilities experienced by patients with leprosy. Understanding the immunopathogenic mechanisms of this disease is essential for interpreting clinical manifestations and conventional diagnostic tests and developing diagnostic strategies for leprosy detection. This review aims to provide an overview of the immune response, clinical features and emerging diagnostic approaches in leprosy.

Source: Transactions of the Royal Society of Tropical Medicine and Hygiene

DOI: 10.1093/trstmh/traf058

Authors: Héctor Serrano-Coll, Lina Restrepo-Rivera, Yicenia Cuadros-Urrego, Nora Cardona-Castro

Institution: Instituto Colombiano de Medicina Tropical

Language: English

Topic: Leprosy Research and Treatment

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,067